diff --git a/drivers/tty/Kconfig b/drivers/tty/Kconfig
index a45d423ad10f02c3a818021bbb18655a8b690500..63a494d36a1fdceba5a7b39f4516060e48af0cc6 100644
--- a/drivers/tty/Kconfig
+++ b/drivers/tty/Kconfig
@@ -220,7 +220,7 @@ config MOXA_INTELLIO
 
 config MOXA_SMARTIO
 	tristate "Moxa SmartIO support v. 2.0"
-	depends on SERIAL_NONSTANDARD && PCI
+	depends on SERIAL_NONSTANDARD && PCI && HAS_IOPORT
 	help
 	  Say Y here if you have a Moxa SmartIO multiport serial card and/or
 	  want to help develop a new version of this driver.
@@ -302,7 +302,7 @@ config GOLDFISH_TTY_EARLY_CONSOLE
 
 config IPWIRELESS
 	tristate "IPWireless 3G UMTS PCMCIA card support"
-	depends on PCMCIA && NETDEVICES
+	depends on PCMCIA && NETDEVICES && HAS_IOPORT
 	select PPP
 	help
 	  This is a driver for 3G UMTS PCMCIA card from IPWireless company. In
diff --git a/drivers/tty/serial/8250/8250_early.c b/drivers/tty/serial/8250/8250_early.c
index 6176083d0341ca10edebe5c4eebfffc922a61472..84242292176570cd2c92afbd4755d303827a4abc 100644
--- a/drivers/tty/serial/8250/8250_early.c
+++ b/drivers/tty/serial/8250/8250_early.c
@@ -46,8 +46,10 @@ static unsigned int serial8250_early_in(struct uart_port *port, int offset)
 		return readl(port->membase + offset);
 	case UPIO_MEM32BE:
 		return ioread32be(port->membase + offset);
+#ifdef CONFIG_HAS_IOPORT
 	case UPIO_PORT:
 		return inb(port->iobase + offset);
+#endif
 	default:
 		return 0;
 	}
@@ -70,9 +72,11 @@ static void serial8250_early_out(struct uart_port *port, int offset, int value)
 	case UPIO_MEM32BE:
 		iowrite32be(value, port->membase + offset);
 		break;
+#ifdef CONFIG_HAS_IOPORT
 	case UPIO_PORT:
 		outb(value, port->iobase + offset);
 		break;
+#endif
 	}
 }
 
diff --git a/drivers/tty/serial/8250/8250_pci.c b/drivers/tty/serial/8250/8250_pci.c
index 6709b6a5f3011db38acc58dc7223158fe4fcf72e..6a638feb44e443a1998980dd037748f227ec1bc8 100644
--- a/drivers/tty/serial/8250/8250_pci.c
+++ b/drivers/tty/serial/8250/8250_pci.c
@@ -156,6 +156,14 @@ static const struct pci_device_id pci_use_msi[] = {
 static int pci_default_setup(struct serial_private*,
 	  const struct pciserial_board*, struct uart_8250_port *, int);
 
+static int serial_8250_need_ioport(struct pci_dev *dev)
+{
+	dev_warn(&dev->dev,
+		 "Serial port not supported because of missing I/O resource\n");
+
+	return -ENXIO;
+}
+
 static void moan_device(const char *str, struct pci_dev *dev)
 {
 	pci_err(dev, "%s\n"
@@ -964,6 +972,9 @@ static int pci_ite887x_init(struct pci_dev *dev)
 	struct resource *iobase = NULL;
 	u32 miscr, uartbar, ioport;
 
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return serial_8250_need_ioport(dev);
+
 	/* search for the base-ioport */
 	for (i = 0; i < ARRAY_SIZE(inta_addr); i++) {
 		iobase = request_region(inta_addr[i], ITE_887x_IOSIZE,
@@ -1514,6 +1525,9 @@ static int pci_quatech_init(struct pci_dev *dev)
 	const struct pci_device_id *match;
 	bool amcc = false;
 
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return serial_8250_need_ioport(dev);
+
 	match = pci_match_id(quatech_cards, dev);
 	if (match)
 		amcc = match->driver_data;
@@ -1538,6 +1552,9 @@ static int pci_quatech_setup(struct serial_private *priv,
 		  const struct pciserial_board *board,
 		  struct uart_8250_port *port, int idx)
 {
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return serial_8250_need_ioport(priv->dev);
+
 	/* Needed by pci_quatech calls below */
 	port->port.iobase = pci_resource_start(priv->dev, FL_GET_BASE(board->flags));
 	/* Set up the clocking */
@@ -1655,6 +1672,9 @@ static int pci_fintek_setup(struct serial_private *priv,
 	u8 config_base;
 	u16 iobase;
 
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return serial_8250_need_ioport(pdev);
+
 	config_base = 0x40 + 0x08 * idx;
 
 	/* Get the io address from configuration space */
@@ -1686,6 +1706,9 @@ static int pci_fintek_init(struct pci_dev *dev)
 	u8 config_base;
 	struct serial_private *priv = pci_get_drvdata(dev);
 
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return serial_8250_need_ioport(dev);
+
 	if (!(pci_resource_flags(dev, 5) & IORESOURCE_IO) ||
 			!(pci_resource_flags(dev, 4) & IORESOURCE_IO) ||
 			!(pci_resource_flags(dev, 3) & IORESOURCE_IO))
@@ -1864,6 +1887,9 @@ static int kt_serial_setup(struct serial_private *priv,
 			   const struct pciserial_board *board,
 			   struct uart_8250_port *port, int idx)
 {
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return serial_8250_need_ioport(priv->dev);
+
 	port->port.flags |= UPF_BUG_THRE;
 	port->port.serial_in = kt_serial_in;
 	port->port.handle_break = kt_handle_break;
@@ -1884,6 +1910,9 @@ pci_wch_ch353_setup(struct serial_private *priv,
 		    const struct pciserial_board *board,
 		    struct uart_8250_port *port, int idx)
 {
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return serial_8250_need_ioport(priv->dev);
+
 	port->port.flags |= UPF_FIXED_TYPE;
 	port->port.type = PORT_16550A;
 	return pci_default_setup(priv, board, port, idx);
@@ -1894,6 +1923,9 @@ pci_wch_ch355_setup(struct serial_private *priv,
 		const struct pciserial_board *board,
 		struct uart_8250_port *port, int idx)
 {
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return serial_8250_need_ioport(priv->dev);
+
 	port->port.flags |= UPF_FIXED_TYPE;
 	port->port.type = PORT_16550A;
 	return pci_default_setup(priv, board, port, idx);
@@ -1904,6 +1936,9 @@ pci_wch_ch38x_setup(struct serial_private *priv,
 		    const struct pciserial_board *board,
 		    struct uart_8250_port *port, int idx)
 {
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return serial_8250_need_ioport(priv->dev);
+
 	port->port.flags |= UPF_FIXED_TYPE;
 	port->port.type = PORT_16850;
 	return pci_default_setup(priv, board, port, idx);
@@ -1918,6 +1953,8 @@ static int pci_wch_ch38x_init(struct pci_dev *dev)
 	int max_port;
 	unsigned long iobase;
 
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return serial_8250_need_ioport(dev);
 
 	switch (dev->device) {
 	case 0x3853: /* 8 ports */
@@ -1937,11 +1974,15 @@ static void pci_wch_ch38x_exit(struct pci_dev *dev)
 {
 	unsigned long iobase;
 
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT)) {
+		serial_8250_need_ioport(dev);
+		return;
+	}
+
 	iobase = pci_resource_start(dev, 0);
 	outb(0x0, iobase + CH384_XINT_ENABLE_REG);
 }
 
-
 static int
 pci_sunix_setup(struct serial_private *priv,
 		const struct pciserial_board *board,
@@ -2052,6 +2093,9 @@ static int pci_moxa_init(struct pci_dev *dev)
 	unsigned int i, num_ports = moxa_get_nports(device);
 	u8 val, init_mode = MOXA_RS232;
 
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return serial_8250_need_ioport(dev);
+
 	if (!(pci_moxa_supported_rs(dev) & MOXA_SUPP_RS232)) {
 		init_mode = MOXA_RS422;
 	}
@@ -2084,6 +2128,9 @@ pci_moxa_setup(struct serial_private *priv,
 	unsigned int bar = FL_GET_BASE(board->flags);
 	int offset;
 
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return serial_8250_need_ioport(priv->dev);
+
 	if (board->num_ports == 4 && idx == 3)
 		offset = 7 * board->uart_offset;
 	else
diff --git a/drivers/tty/serial/8250/8250_pcilib.c b/drivers/tty/serial/8250/8250_pcilib.c
index ea906d721b2c3eac15c9e8d62cc6fa56c3ef6150..fc1882d7515b5814ff1240ffdbe1009ab908ad6b 100644
--- a/drivers/tty/serial/8250/8250_pcilib.c
+++ b/drivers/tty/serial/8250/8250_pcilib.c
@@ -28,6 +28,10 @@ int serial8250_pci_setup_port(struct pci_dev *dev, struct uart_8250_port *port,
 		port->port.membase = pcim_iomap_table(dev)[bar] + offset;
 		port->port.regshift = regshift;
 	} else {
+		if (!IS_ENABLED(CONFIG_HAS_IOPORT)) {
+			pr_err("Serial port %lx requires I/O port support\n", port->port.iobase);
+			return -EINVAL;
+		}
 		port->port.iotype = UPIO_PORT;
 		port->port.iobase = pci_resource_start(dev, bar) + offset;
 		port->port.mapbase = 0;
diff --git a/drivers/tty/serial/8250/8250_port.c b/drivers/tty/serial/8250/8250_port.c
index 3509af7dc52b8816f2f5ab58f0d999696f7483e7..74717675dc41db6a5b5b0dd1da84b4ea23bd9928 100644
--- a/drivers/tty/serial/8250/8250_port.c
+++ b/drivers/tty/serial/8250/8250_port.c
@@ -338,6 +338,7 @@ static void default_serial_dl_write(struct uart_8250_port *up, u32 value)
 	serial_out(up, UART_DLM, value >> 8 & 0xff);
 }
 
+#ifdef CONFIG_HAS_IOPORT
 static unsigned int hub6_serial_in(struct uart_port *p, int offset)
 {
 	offset = offset << p->regshift;
@@ -351,6 +352,7 @@ static void hub6_serial_out(struct uart_port *p, int offset, int value)
 	outb(p->hub6 - 1 + offset, p->iobase);
 	outb(value, p->iobase + 1);
 }
+#endif /* CONFIG_HAS_IOPORT */
 
 static unsigned int mem_serial_in(struct uart_port *p, int offset)
 {
@@ -400,6 +402,7 @@ static unsigned int mem32be_serial_in(struct uart_port *p, int offset)
 	return ioread32be(p->membase + offset);
 }
 
+#ifdef CONFIG_HAS_IOPORT
 static unsigned int io_serial_in(struct uart_port *p, int offset)
 {
 	offset = offset << p->regshift;
@@ -411,6 +414,23 @@ static void io_serial_out(struct uart_port *p, int offset, int value)
 	offset = offset << p->regshift;
 	outb(value, p->iobase + offset);
 }
+#endif
+static unsigned int no_serial_in(struct uart_port *p, int offset)
+{
+	return (unsigned int)-1;
+}
+
+static void no_serial_out(struct uart_port *p, int offset, int value)
+{
+}
+
+static __always_inline bool is_upf_fourport(struct uart_port *port)
+{
+	if (!IS_ENABLED(CONFIG_HAS_IOPORT))
+		return false;
+
+	return port->flags & UPF_FOURPORT;
+}
 
 static int serial8250_default_handle_irq(struct uart_port *port);
 
@@ -422,10 +442,12 @@ static void set_io_from_upio(struct uart_port *p)
 	up->dl_write = default_serial_dl_write;
 
 	switch (p->iotype) {
+#ifdef CONFIG_HAS_IOPORT
 	case UPIO_HUB6:
 		p->serial_in = hub6_serial_in;
 		p->serial_out = hub6_serial_out;
 		break;
+#endif
 
 	case UPIO_MEM:
 		p->serial_in = mem_serial_in;
@@ -446,11 +468,16 @@ static void set_io_from_upio(struct uart_port *p)
 		p->serial_in = mem32be_serial_in;
 		p->serial_out = mem32be_serial_out;
 		break;
-
-	default:
+#ifdef CONFIG_HAS_IOPORT
+	case UPIO_PORT:
 		p->serial_in = io_serial_in;
 		p->serial_out = io_serial_out;
 		break;
+#endif
+	default:
+		WARN(1, "Unsupported UART type %x\n", p->iotype);
+		p->serial_in = no_serial_in;
+		p->serial_out = no_serial_out;
 	}
 	/* Remember loaded iotype */
 	up->cur_iotype = p->iotype;
@@ -1174,7 +1201,7 @@ static void autoconfig(struct uart_8250_port *up)
 		 */
 		scratch = serial_in(up, UART_IER);
 		serial_out(up, UART_IER, 0);
-#ifdef __i386__
+#if defined(__i386__) && defined(CONFIG_HAS_IOPORT)
 		outb(0xff, 0x080);
 #endif
 		/*
@@ -1183,7 +1210,7 @@ static void autoconfig(struct uart_8250_port *up)
 		 */
 		scratch2 = serial_in(up, UART_IER) & UART_IER_ALL_INTR;
 		serial_out(up, UART_IER, UART_IER_ALL_INTR);
-#ifdef __i386__
+#if defined(__i386__) && defined(CONFIG_HAS_IOPORT)
 		outb(0, 0x080);
 #endif
 		scratch3 = serial_in(up, UART_IER) & UART_IER_ALL_INTR;
@@ -1306,12 +1333,12 @@ static void autoconfig_irq(struct uart_8250_port *up)
 {
 	struct uart_port *port = &up->port;
 	unsigned char save_mcr, save_ier;
+	unsigned long irqs;
 	unsigned char save_ICP = 0;
 	unsigned int ICP = 0;
-	unsigned long irqs;
 	int irq;
 
-	if (port->flags & UPF_FOURPORT) {
+	if (is_upf_fourport(port)) {
 		ICP = (port->iobase & 0xfe0) | 0x1f;
 		save_ICP = inb_p(ICP);
 		outb_p(0x80, ICP);
@@ -1330,7 +1357,7 @@ static void autoconfig_irq(struct uart_8250_port *up)
 	irqs = probe_irq_on();
 	serial8250_out_MCR(up, 0);
 	udelay(10);
-	if (port->flags & UPF_FOURPORT) {
+	if (is_upf_fourport(port)) {
 		serial8250_out_MCR(up, UART_MCR_DTR | UART_MCR_RTS);
 	} else {
 		serial8250_out_MCR(up,
@@ -1354,7 +1381,7 @@ static void autoconfig_irq(struct uart_8250_port *up)
 	serial_out(up, UART_IER, save_ier);
 	uart_port_unlock_irq(port);
 
-	if (port->flags & UPF_FOURPORT)
+	if (is_upf_fourport(port))
 		outb_p(save_ICP, ICP);
 
 	port->irq = (irq > 0) ? irq : 0;
@@ -2435,7 +2462,7 @@ int serial8250_do_startup(struct uart_port *port)
 	 */
 	up->ier = UART_IER_RLSI | UART_IER_RDI;
 
-	if (port->flags & UPF_FOURPORT) {
+	if (is_upf_fourport(port)) {
 		unsigned int icp;
 		/*
 		 * Enable interrupts on the AST Fourport board
@@ -2480,7 +2507,7 @@ void serial8250_do_shutdown(struct uart_port *port)
 		serial8250_release_dma(up);
 
 	uart_port_lock_irqsave(port, &flags);
-	if (port->flags & UPF_FOURPORT) {
+	if (is_upf_fourport(port)) {
 		/* reset interrupts on the AST Fourport board */
 		inb((port->iobase & 0xfe0) | 0x1f);
 		port->mctrl |= TIOCM_OUT1;
diff --git a/drivers/tty/serial/8250/Kconfig b/drivers/tty/serial/8250/Kconfig
index 47ff50763c048c89b19b7c9f13f462bc5368ab43..1eb20350fcf432d41cb416bed3be72ed8ab129bb 100644
--- a/drivers/tty/serial/8250/Kconfig
+++ b/drivers/tty/serial/8250/Kconfig
@@ -72,7 +72,7 @@ config SERIAL_8250_16550A_VARIANTS
 
 config SERIAL_8250_FINTEK
 	bool "Support for Fintek variants"
-	depends on SERIAL_8250
+	depends on SERIAL_8250 && HAS_IOPORT
 	help
 	  Selecting this option will add support for the RS232 and RS485
 	  capabilities of the Fintek F81216A LPC to 4 UART as well similar
@@ -163,7 +163,7 @@ config SERIAL_8250_HP300
 
 config SERIAL_8250_CS
 	tristate "8250/16550 PCMCIA device support"
-	depends on PCMCIA && SERIAL_8250
+	depends on PCMCIA && SERIAL_8250 && HAS_IOPORT
 	help
 	  Say Y here to enable support for 16-bit PCMCIA serial devices,
 	  including serial port cards, modems, and the modem functions of
diff --git a/drivers/tty/serial/Kconfig b/drivers/tty/serial/Kconfig
index 28e4beeabf8f373fc76e09ea7d1c9d55a66f4964..45f0f779fbf960e9fa66375dbc44c379edc63bef 100644
--- a/drivers/tty/serial/Kconfig
+++ b/drivers/tty/serial/Kconfig
@@ -877,7 +877,7 @@ config SERIAL_TXX9_STDSERIAL
 
 config SERIAL_JSM
 	tristate "Digi International NEO and Classic PCI Support"
-	depends on PCI
+	depends on PCI && HAS_IOPORT
 	select SERIAL_CORE
 	help
 	  This is a driver for Digi International's Neo and Classic series
