diff --git a/docs/about/deprecated.rst b/docs/about/deprecated.rst
index 2f51cf770a..3b074b9ed4 100644
--- a/docs/about/deprecated.rst
+++ b/docs/about/deprecated.rst
@@ -20,20 +20,6 @@ they were first deprecated in the 2.10.0 release.
 What follows is a list of all features currently marked as
 deprecated.
 
-Build options
--------------
-
-``gprof`` builds (since 8.0)
-''''''''''''''''''''''''''''
-
-The ``--enable-gprof`` configure setting relies on compiler
-instrumentation to gather its data which can distort the generated
-profile. As other non-instrumenting tools are available that give a
-more holistic view of the system with non-instrumented binaries we are
-deprecating the build option and no longer defend it in CI. The
-``--enable-gcov`` build option remains for analysis test case
-coverage.
-
 System emulator command line arguments
 --------------------------------------
 
diff --git a/meson.build b/meson.build
index 12df8fe0de..b8bb69f9ea 100644
--- a/meson.build
+++ b/meson.build
@@ -254,11 +254,6 @@ if host_arch == 'i386' and not cc.links('''
   qemu_common_flags = ['-march=i486'] + qemu_common_flags
 endif
 
-if get_option('gprof')
-  qemu_common_flags += ['-p']
-  qemu_ldflags += ['-p']
-endif
-
 if get_option('prefer_static')
   qemu_ldflags += get_option('b_pie') ? '-static-pie' : '-static'
 endif
@@ -2214,7 +2209,6 @@ config_host_data.set('CONFIG_DEBUG_GRAPH_LOCK', get_option('debug_graph_lock'))
 config_host_data.set('CONFIG_DEBUG_MUTEX', get_option('debug_mutex'))
 config_host_data.set('CONFIG_DEBUG_STACK_USAGE', get_option('debug_stack_usage'))
 config_host_data.set('CONFIG_DEBUG_TCG', get_option('debug_tcg'))
-config_host_data.set('CONFIG_GPROF', get_option('gprof'))
 config_host_data.set('CONFIG_LIVE_BLOCK_MIGRATION', get_option('live_block_migration').allowed())
 config_host_data.set('CONFIG_QOM_CAST_DEBUG', get_option('qom_cast_debug'))
 config_host_data.set('CONFIG_REPLICATION', get_option('replication').allowed())
@@ -4128,12 +4122,6 @@ summary_info += {'memory allocator':  get_option('malloc')}
 summary_info += {'avx2 optimization': config_host_data.get('CONFIG_AVX2_OPT')}
 summary_info += {'avx512bw optimization': config_host_data.get('CONFIG_AVX512BW_OPT')}
 summary_info += {'avx512f optimization': config_host_data.get('CONFIG_AVX512F_OPT')}
-if get_option('gprof')
-  gprof_info = 'YES (deprecated)'
-else
-  gprof_info = get_option('gprof')
-endif
-summary_info += {'gprof':             gprof_info}
 summary_info += {'gcov':              get_option('b_coverage')}
 summary_info += {'thread sanitizer':  get_option('tsan')}
 summary_info += {'CFI support':       get_option('cfi')}
diff --git a/bsd-user/bsd-proc.h b/bsd-user/bsd-proc.h
index a1061bffb8..0e1d461c4c 100644
--- a/bsd-user/bsd-proc.h
+++ b/bsd-user/bsd-proc.h
@@ -25,9 +25,6 @@
 /* exit(2) */
 static inline abi_long do_bsd_exit(void *cpu_env, abi_long arg1)
 {
-#ifdef TARGET_GPROF
-    _mcleanup();
-#endif
     gdb_exit(arg1);
     qemu_plugin_user_exit();
     _exit(arg1);
diff --git a/bsd-user/signal.c b/bsd-user/signal.c
index dc5ad06a78..9ebff382f6 100644
--- a/bsd-user/signal.c
+++ b/bsd-user/signal.c
@@ -848,11 +848,6 @@ void signal_init(void)
     act.sa_flags = SA_SIGINFO;
 
     for (i = 1; i <= TARGET_NSIG; i++) {
-#ifdef CONFIG_GPROF
-        if (i == TARGET_SIGPROF) {
-            continue;
-        }
-#endif
         host_sig = target_to_host_signal(i);
         sigaction(host_sig, NULL, &oact);
         if (oact.sa_sigaction == (void *)SIG_IGN) {
diff --git a/linux-user/exit.c b/linux-user/exit.c
index 3017d28a3c..50266314e0 100644
--- a/linux-user/exit.c
+++ b/linux-user/exit.c
@@ -22,9 +22,6 @@
 #include "qemu.h"
 #include "user-internals.h"
 #include "qemu/plugin.h"
-#ifdef CONFIG_GPROF
-#include <sys/gmon.h>
-#endif
 
 #ifdef CONFIG_GCOV
 extern void __gcov_dump(void);
@@ -32,9 +29,6 @@ extern void __gcov_dump(void);
 
 void preexit_cleanup(CPUArchState *env, int code)
 {
-#ifdef CONFIG_GPROF
-        _mcleanup();
-#endif
 #ifdef CONFIG_GCOV
         __gcov_dump();
 #endif
diff --git a/linux-user/signal.c b/linux-user/signal.c
index a7ba2ccaf4..a67ab47d30 100644
--- a/linux-user/signal.c
+++ b/linux-user/signal.c
@@ -588,11 +588,6 @@ void signal_init(void)
     act.sa_flags = SA_SIGINFO;
     act.sa_sigaction = host_signal_handler;
     for(i = 1; i <= TARGET_NSIG; i++) {
-#ifdef CONFIG_GPROF
-        if (i == TARGET_SIGPROF) {
-            continue;
-        }
-#endif
         host_sig = target_to_host_signal(i);
         sigaction(host_sig, NULL, &oact);
         if (oact.sa_sigaction == (void *)SIG_IGN) {
diff --git a/meson_options.txt b/meson_options.txt
index 57e265c871..6a17b90968 100644
--- a/meson_options.txt
+++ b/meson_options.txt
@@ -348,9 +348,6 @@ option('debug_stack_usage', type: 'boolean', value: false,
        description: 'measure coroutine stack usage')
 option('qom_cast_debug', type: 'boolean', value: true,
        description: 'cast debugging support')
-option('gprof', type: 'boolean', value: false,
-       description: 'QEMU profiling with gprof',
-       deprecated: true)
 option('slirp_smbd', type : 'feature', value : 'auto',
        description: 'use smbd (at path --smbd=*) in slirp networking')
 
diff --git a/scripts/meson-buildoptions.sh b/scripts/meson-buildoptions.sh
index e4b46d5715..2a74b0275b 100644
--- a/scripts/meson-buildoptions.sh
+++ b/scripts/meson-buildoptions.sh
@@ -34,7 +34,6 @@ meson_options_help() {
   printf "%s\n" '                           (choices: auto/disabled/enabled/internal/system)'
   printf "%s\n" '  --enable-fuzzing         build fuzzing targets'
   printf "%s\n" '  --enable-gcov            Enable coverage tracking.'
-  printf "%s\n" '  --enable-gprof           QEMU profiling with gprof'
   printf "%s\n" '  --enable-lto             Use link time optimization'
   printf "%s\n" '  --enable-malloc=CHOICE   choose memory allocator to use [system] (choices:'
   printf "%s\n" '                           jemalloc/system/tcmalloc)'
@@ -309,8 +308,6 @@ _meson_option_parse() {
     --disable-glusterfs) printf "%s" -Dglusterfs=disabled ;;
     --enable-gnutls) printf "%s" -Dgnutls=enabled ;;
     --disable-gnutls) printf "%s" -Dgnutls=disabled ;;
-    --enable-gprof) printf "%s" -Dgprof=true ;;
-    --disable-gprof) printf "%s" -Dgprof=false ;;
     --enable-gtk) printf "%s" -Dgtk=enabled ;;
     --disable-gtk) printf "%s" -Dgtk=disabled ;;
     --enable-gtk-clipboard) printf "%s" -Dgtk_clipboard=enabled ;;
diff --git a/tests/qemu-iotests/meson.build b/tests/qemu-iotests/meson.build
index 44761e1e4d..53847cb98f 100644
--- a/tests/qemu-iotests/meson.build
+++ b/tests/qemu-iotests/meson.build
@@ -1,4 +1,4 @@
-if not have_tools or targetos == 'windows' or get_option('gprof')
+if not have_tools or targetos == 'windows'
   subdir_done()
 endif
 
